Bosutinib
Bosutinib is a tablet that you take by mouth. It works as follows:-
Bosutinib is a type of medication that blocks certain proteins in the body that are involved in cancer growth. Specifically, it targets a protein called BCR-ABL kinase, which plays a key role in a type of leukemia called chronic myelogenous leukemia (CML). Bosutinib also works against other proteins called Src kinases, which are linked to the spread and growth of cancer cells. While it has some effect on other proteins like platelet-derived growth factor receptor (PDGFR) and protein-tyrosine kinase Kit (cKIT), its main action is on BCR-ABL kinase and Src kinases. Bosutinib is effective against both imatinib-sensitive and resistant leukemia cells, slowing down their growth and survival.
Have any queries, book a consultation with our Oncology Clinical SpecialistPrimary uses are to treat Leukemia, chronic myelogenous.
Research studies are going on this drug to check if this medicine can be used to treat other type of cancer.
Visit our Research Division Doctors in Online Consults for more details.
If you miss a dose of bosutinib, take it as soon as you can if it is within 12 hours of the missed dose. If it is more than 12 hours since your missed dose, skip the missed dose and go back to your usual dosing times.
If you vomit the dose of bosutinib, do not take a second dose. Let your doctor know as a medication to prevent nausea may be required for future doses.
Have any queries, book a consultation with our Oncology Clinical Specialist
Anemia, Low white blood cells count, Low platelet count, Abdominal pain, Diarrhea, Nausea, Vomiting, Infections, Liver enzymes increase, Headache.
Have any queries, book a consultation with our Oncology Clinical Specialist
Other drugs such as Ketoconazole , Aprepitant , Rifampin, Lansoprazole and Antacids may interact with bosutinib. Tell your doctor if you are taking these or any other drugs as you may need extra blood tests or your dose may need to be changed.
Have any queries, book a consultation with our Oncology Clinical Specialist
Bosutinib may cause sterility in men. If you plan to have children, discuss this with your doctor before being treated with bosutinib. • Bosutinib may damage sperm and may harm the baby if used during pregnancy. It is best to use birth control while being treated with bosutinib and for 4 weeks after treatment. Tell your doctor right away if you or your partner becomes pregnant. Do not breastfeed during treatment.
Have any queries, book a consultation with our Oncology Clinical Specialist
