Cabozantinib

Cabozantinib is a tablet that you take by mouth. It works as follows:- 

Cabozantinib is a medication taken by mouth, consisting of small molecules that act as inhibitors of tyrosine kinases. These enzymes include hepatocyte growth factor receptor protein (MET), vascular endothelial growth factor (VEGF), and fms-like tyrosine kinase-3 (FLT3). By targeting these receptors, cabozantinib prompts cancer cell death, inhibits tumor growth, prevents the formation of new blood vessels (angiogenesis), and reduces the spread of cancer to other parts of the body (metastasis).

Have any queries, book a consultation with our Oncology Clinical Specialist

Primary uses are to treat Renal cell cancer, Liver cancer.

Secondarily this drug is also used to treat Thyroid cancer.

Research studies are going on this drug to check if this medicine can be used to treat other type of cancer. 

Visit our Research Division Doctors in Online Consults for more details.

If you miss a dose of cabozantinib, take it as soon as you can if it is within 12 hours of the missed dose. If it is more than 12 hours since your missed dose, skip the missed dose and go back to your usual dosing times.

If you vomit the dose of cabozantinib, do not take a second dose. Call your doctor during office hours for advice. You will be told whether you need to take another dose.

Have any queries, book a consultation with our Oncology Clinical Specialist.

Anemia, Low white blood cell count, Underactive Thyroid, Diarrhea, Mouth sores or Mouth ulcers, Nausea, Fatigue, Severe weight loss due to lack of appetite, Low calcium, pottasium and magnesium levels, Dizziness, Rash, Hypertension.

 

Have any queries, book a consultation with our Oncology Clinical Specialist

Other drugs such as Ketoconazole and Rifampin may interact with cabozantinib. Tell your doctor if you are taking these or any other drugs as you may need extra blood tests or your dose may need to be changed.

 

Have any queries, book a consultation with our Oncology Clinical Specialist

 

 

Cabozantinib may affect fertility in men and women. If you plan to have children, discuss this with your doctor before being treated with cabozantinib.

Cabozantinib may damage sperm and may harm the baby if used during pregnancy. It is best to use birth control while being treated with cabozantinib and for at least four months after your last dose. Hormonal birth control may not work as well while you are taking cabozantinib. Talk to your doctor about which birth control options are best for you. Tell your doctor right away if you or your partner becomes pregnant. Do not breastfeed during treatment.

 

Have any queries, book a consultation with our Oncology Clinical Specialist