Ceritinib

Ceritinib is a capsule that you take by mouth. It works as follows:- 

Ceritinib is an advanced medication taken by mouth, designed to specifically target a protein called anaplastic lymphoma kinase (ALK), which is found in certain cancer cells. By blocking ALK, ceritinib stops the activation of proteins involved in cancer cell growth, ultimately preventing the spread of cancer. Additionally, ceritinib inhibits other receptors like insulin-like growth factor 1 receptor, insulin receptor, and ROS1. Compared to older medications like crizotinib, ceritinib is significantly more potent against ALK and is better at penetrating the brain, making it effective against various mutations that cause resistance to crizotinib.
Have any queries, book a consultation with our Oncology Clinical Specialist

Primary uses are to treat Lung cancer, non-small cell. 

Research studies are going on this drug to check if this medicine can be used to treat other type of cancer. 

Visit our Research Division Doctors in Online Consults for more details.

If you miss a dose of ceritinib, take it as soon as you can if it is within 12 hours of the missed dose. If it is more than 12 hours since your missed dose, skip the missed dose and go back to your usual dosing times.

If you vomit the dose of ceritinib, do not take a second dose. Call your doctor during office hours for advice as a medication to prevent nausea may be required for future doses.

Have any queries, book a consultation with our Oncology Clinical Specialist

Anemia, Slow heartbeat, Vision disorders, Diarrhea, Nausea, Vomiting, Fatigue, Liver enzyme (ALT and AST) increase, Nerve damage or pain, Rash, Shortness of breath.

 

Have any queries, book a consultation with our Oncology Clinical Specialist

Other drugs such as Ketoconazole and Rifampin may interact with ceritinib. Check with our doctor or pharmacist for further instructions if you are taking drugs to reduce stomach acid such as Ranitidine or Calcium Carbonate . Tell your doctor if you are taking these or any other drugs as you may need extra blood tests or your dose may need to be changed.

 

Have any queries, book a consultation with our Oncology Clinical Specialist

 

 

Ceritinib may damage sperm and may harm the baby if used during pregnancy. It is best to use birth control while being treated with ceritinib and for 3 months after stopping treatment. Tell your doctor right away if you or your partner becomes pregnant. Do not breastfeed during treatment.

 

Have any queries, book a consultation with our Oncology Clinical Specialist