Cetuximab
Cetuximab is a clear liquid that is injected into a vein. It works as follows:-
Cetuximab is a specialized antibody designed to target and bind to a protein called the epidermal growth factor receptor (EGFR) in the body. By attaching to EGFR, cetuximab prevents the activation of certain enzymes associated with cell growth, leading to a slowdown in cell growth, increased cell death, and reduced production of vascular endothelial growth factor. Additionally, cetuximab prompts the internalization and breakdown of EGFR, further reducing its activity. However, it's important to note that mutations in the K-ras gene within tumor cells may impact cetuximab's effectiveness. Interestingly, cetuximab can also boost the effectiveness of radiation therapy by blocking EGFR signaling. This medication primarily works by halting cell cycle progression at the G1 phase.
Have any queries, book a consultation with our Oncology Clinical SpecialistPrimary uses are to treat Colorectal cancer, Head and neck cancer.
Secondarily this drug is also used to treat Lung cancer, non-small cell, Skin cancer, squamous cell
Research studies are going on this drug to check if this medicine can be used to treat other type of cancer.
Visit our Research Division Doctors in Online Consults for more details.
Cetuximab is given by an injection. Please book a consultation with our Oncology Clinical Specialist to know more about what to do if you miss the dose.
Infusion reactions, Feeling weak and tired, Fever, Pimples or Rash, Nail changes, Constipation, Diarrhea, Nausea, Vomiting, Headache, Abdominal pain, Shortness of breath.
Have any queries, book a consultation with our Oncology Clinical Specialist
Other drugs such as Cisplatin, Doxorubicin, Gemcitabine, Irinotecan, Paclitaxel. Tell your doctor if you are taking these or any other drugs as you may need extra blood tests or your dose may need to be changed.
Have any queries, book a consultation with our Oncology Clinical Specialist
Cetuximab may damage sperm and may harm the baby if used during pregnancy. It is best to use birth control while being treated with cetuximab. Tell your doctor right away if you or your partner becomes pregnant. Do not breast feed during treatment.
Have any queries, book a consultation with our Oncology Clinical Specialist
