Venetoclax is a medication used to treat a type of blood cancer called chronic lymphocytic leukemia (CLL) and certain types of lymphomas. CLL is a cancer that affects a type of white blood cell called lymphocytes, which are crucial for the body's immune system. Lymphoma, on the other hand, is a cancer that affects the lymphatic system, a part of the body's immune system.
Venetoclax belongs to a class of drugs called BCL-2 inhibitors. BCL-2 is a protein that helps regulate cell death, and in cancer cells, including those found in CLL and certain lymphomas, there is often an overproduction of this protein. This overproduction of BCL-2 allows cancer cells to survive and grow unchecked.
Venetoclax works by specifically targeting and blocking the activity of the BCL-2 protein. By doing so, it helps trigger a process called apoptosis, which is a natural way for the body to get rid of damaged or unwanted cells, including cancer cells. Essentially, Venetoclax helps to restore the body's ability to control cell death, allowing cancer cells to be eliminated more effectively.
Before starting treatment with Venetoclax, patients undergo tests to determine if they have specific genetic mutations, such as the 17p deletion, that make them eligible for this treatment. These tests help identify patients who are most likely to benefit from Venetoclax therapy.
Venetoclax is usually taken orally in the form of tablets, once daily, with or without food, as directed by a healthcare provider. The dosage may vary depending on factors such as the patient's weight, age, and overall health status. It's essential to take Venetoclax exactly as prescribed and not to miss any doses.
Like all medications, Venetoclax can cause side effects, which can vary from person to person. Common side effects of Venetoclax may include nausea, diarrhea, vomiting, fatigue, and upper respiratory tract infections. These side effects are usually manageable and may improve over time as the body adjusts to the medication.
In some cases, Venetoclax may cause more severe side effects that require medical attention. These can include low white blood cell counts (neutropenia), low platelet counts (thrombocytopenia), and an increased risk of infections.
Patients receiving Venetoclax treatment are closely monitored by their healthcare providers through regular follow-up appointments, blood tests, and imaging scans. These checks help ensure that treatment is effective and well-tolerated, and allow for early detection and management of any potential side effects.
In conclusion, Venetoclax is a medication used to treat chronic lymphocytic leukemia (CLL) and certain types of lymphomas by targeting a specific protein called BCL-2. By blocking the activity of BCL-2, Venetoclax helps trigger cell death in cancer cells, ultimately improving the patient's condition. While Venetoclax can be an effective treatment option for many patients, it's essential to be aware of the potential side effects and communicate openly with your healthcare provider throughout your treatment.
Have any queries, book a consultation with our Oncology Clinical Specialist
Venetoclax
Venetoclax is a medicine that helps treat certain types of blood cancer, like chronic lymphocytic leukemia (CLL) and certain lymphomas. It works by targeting a specific protein in cancer cells called BCL-2.
In cancer cells, this BCL-2 protein helps them survive and grow when they shouldn't. Venetoclax blocks this protein's action, which makes the cancer cells die naturally. Essentially, it helps the body's own defenses get rid of the cancer cells more effectively.
So, Venetoclax helps stop cancer cells from growing and spreading, giving patients a better chance of beating their cancer.
Have any queries, book a consultation with our Oncology Clinical Specialist